From 1842 to 1855, Har Sinai Congregation was led solely by laypersons, a trend typical of American Jewish life in this period. The Congregation moved from one place to another in Baltimore for “worship, study and fellowship.”

Rabbinic leadership began in 1855 as follows.
David Einhorn, 1855-1861
Solomon Deutsch, 1862-1874
Jacob Mayer, 1874-1876
Emil Hirsch, 1877-1878
Samuel Sale, 1878-1883
David Philipson, 1883-1888
Tobias Schanfarber, 1888-1898
Charles Rubenstein, 1898-1920
Louis Bernstein, 1920-1922
Edward Israel, 1923-1941
Abraham Shusterman, 1941-1972
Howard Simon, 1972-1973
Herbert Rutman, 1973-1981
Floyd Herman, 1981-2003
Bradd Boxman, 2003-2009
Darryl Crystal, 2009-2010
Benjamin Sharff, 2010-2016
Linda Joseph, 2016 to the present